Posted by blueberry1 on January 4, 2007, at 14:36:35
In reply to Triple Re-uptake inhibitors- why so excited?, posted by Jimmyboy on January 4, 2007, at 13:42:08
I think all the drugs work in such complicated ways, especially at molecular levels that are not recognized or understood versus the overall effect they do. For example, I sometimes wonder if it is those unrecognized things that does the healing and that, say for example with ssris, it is the serotonin reuptake that gives the side effects but not the healing. That could explain why 4 ssris won't work for someone but a 5th will be a miracle...it wasn't lack of serotonin, it was something else unique to the drug.
The drugs all act in different parts of the brain, with varying intensity in those different parts, and they have an impact on how genes talk to each other, how receptors talk to each other, calcium, magnesium, potassium currents, and all kinds of weird stuff that I do not understand. And likely the high powered scientists don't understand either.
The idea of a triple reuptake inhibitor is in my opinion a grasp at more profits but not necessarily more healing. I would bet a new triple reuptake inhibitor would have about the same clinical efficacy as anything else (not great) and probably more side effects. Just a hunch though.
Since parnate and nardil basically do the same thing, then why will one work great and the other not? Or neither works at all?
And it is my humble opinion that most of us do not have a lack of serotonin or other neuros. I think the whole idea of marinating a brain in high density neurotransmitters is flawed. If it was accurate, then all someone would need to do is take 5htp and tyrosine supplements. A triple reuptake inhibitor just takes that whole flawed theory one step further. The ultimate goal is a new profit generator.
These opinions of mine are highly debateable I realize. I'm very glad that some people do find their meds to be miracles. And I'm very glad there will be new ones to offer the same potential. I am afraid though that any new one, based on old theories, will be a blockbuster in sales but not a blockbuster in actual reliable healing.
I do not mean to sound skeptical so please don't take it that way. I just think they need brand new blockbuster theories in the causes of depression, not new versions of old drugs.
poster:blueberry1
thread:719292
URL: http://www.dr-bob.org/babble/20070101/msgs/719317.html