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Re: Are MAOIs worth it?

Posted by djmmm on January 4, 2007, at 9:10:52

In reply to Re: Are MAOIs worth it? » Karen44, posted by Quintal on January 4, 2007, at 0:45:27

> >Parnate has amphetamine-like qualities.
>
> The old Parnate methamphetamine metabolite debate? There's still much confusion over that but I found Parnate did have an amphetamine-like feel to it at high doses. Amphetamine metabolites have been found in the blood and urine of Parnate overdoses and people have posted here to say they have tested positive for amphetamines while taking Parnate.
>
> At 120mg I had the dilated pupils, racing heart, erect nipples and gooseflesh characteristic of 'crystal meth'. I wonder if going back to it would help my fatigue?
>
> Q

I think some of the "amphetamine metabolite" confusion is because Parnate is so structurally similar to the amphetamines/pheynylethyamines, that the more "non-specific" drug tests pick it up-- as a false positive.

A lot of the physical effects of what you may attribute to an amphetamine metabolite, may simply be the result of a spike in blood pressure, or the catecholamine enhansing effects of Parnate itself. Im guessing, the amount of Amphetamine/Methamphetamine derived as a metabolite, would have to be VERY high to elicit a "meth-like" response (thus the reported presense of amphetamine metabolites in overdose)


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URL: http://www.dr-bob.org/babble/20070101/msgs/719224.html