Posted by yxibow on September 19, 2006, at 22:34:08
In reply to Re: Parnate and gaba, posted by willyee on September 19, 2006, at 21:04:37
> > > I dont know why i did it this way,but here is a file,in a screen shot speaking about parnate and a up regulation on gaba,i was unaware that it even effected gaba at all.
> > >
> > > Its a screen shot,but definatly large enough to read,im at awe where this site gets its information,its so much,and it seems to be similiar so it doesen appear its a collection of various work,rather comming from a single place.
> > >
> > > http://img212.imageshack.us/img212/4277/fileyb7.jpg
> > >
> > >
> > > either click the link or paste it.
> >
> >
> > GABA-B is somewhat different than GABA-A. The structures and ions that surround it are different, and the main drug that acts on it is baclofen, not benzodiazepines.
>
> Yeah i remember hearing this,but isnt both A-B involved in sedation or anxiety relieaf,the benzo one obviously more so.GABA-A has its own receptor subtypes (4 main ones exemplified in GABA-BZ, benzodiazepines involved in varying amounts of sedative-hypnotic, anaesthetic, anxiolytic, and anti-spasmotic responses). GABA-B primarily has one agnonist, baclofen, although it is thought that it could be a site for pain modulation
http://www.biotrend.com/pdf/gabarev.pdf
> Isnt GHB one that acts on the opposite receptor of benzos.Yes, GHB acts on its own receptor as well as GABA-B.
poster:yxibow
thread:687430
URL: http://www.dr-bob.org/babble/20060919/msgs/687553.html