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Re: MAOI and responsibility » kimcrazylady

Posted by jedi on August 17, 2006, at 12:15:32

In reply to Re: MAOI and responsibility, posted by kimcrazylady on August 17, 2006, at 11:28:32

> I have been on Parnate forever, and I use protein powders without problems. I make a thick shake in the morning as my breakfast.
>
> I use Spiru-tein and have for years without problems.
>
> Hope that helps.
>
> Kim

Hi Kim,
I really know nothing about protein powders so I plead ignorant on that one. However, H. Upmann said "I know that the whey protein powder has a listed value of 200+ mg's for tyramine which common sense would tell you to stay clear." The research studies use 6mg of tyramine to denote a dangerous level. I have read that 10mg can cause a minor hypertensive event and 25mg can cause a major crisis. From this information, I conclude that any substance with 200mg of tyramine per serving will cause a major hypertensive crisis for most people taking an irreversible MAOI.
Take care,
Jedi

Source:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=Retrieve&dopt=abstractplus&list_uids=8889911

J Clin Psychopharmacol. 1996 Oct;16(5):383-8.

Tyramine content of previously restricted foods in monoamine oxidase inhibitor diets.

Walker SE, Shulman KI, Tailor SA, Gardner D.
Department of Pharmacy, Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.

Traditional monoamine oxidase inhibitors (MAOIs) remain an important class of drugs for a variety of psychiatric conditions, including depressive illnesses, anxiety, and eating disorders. It was the objective of this study to refine the MAOI diet by determining the tyramine content of a variety of untested and "controversial" foods that continue to appear on MAOI diet-restricted food lists. A secondary objective of the study was to evaluate the effect of freshness on the tyramine content of some foods. Fifty-one food samples were evaluated for tyramine content by liquid chromatography. Food samples included a selection of sausages, beverages, sliced meat products, including chicken liver, and some fruits, including raspberries, bananas, and banana peels. Foods that were found to have dangerously high concentrations of tyramine (> or = 6 mg/serving) included chicken liver aged 9 days (63.84 mg/30 g), air-dried sausage (7.56 g/30 g), soy sauce (0.941 mg/ml), and sauerkraut (7.75 mg/250 g). Of the foods analyzed in this study, only those with high tyramine content per serving should continue to be absolutely restricted. All other foods are either safe for consumption or safe in moderation. The data provided should be combined with the data from other similar analytical studies to develop a list of foods that should be absolutely restricted. A more accurate list of restricted foods may enhance patient dietary compliance.

PMID: 8889911 [PubMed - indexed for MEDLINE]


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