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Re: MAOI's and blood pressure meds

Posted by SLS on August 3, 2006, at 8:22:13

In reply to Re: MAOI's and blood pressure meds » H. Upmann, posted by jedi on August 3, 2006, at 1:56:40

> Many doctors no long prescribe the "bite and swallow" nifedipine capsules because of the chance of a greatly lowered BP. This actually happened to me once. The tyramine reaction has a shorter duration than the nifedipine, leaving some people with a dangerously low blood pressure. When this happened to me, my PDOC at the time had prescribed 20mg capsules of nifedipine. This was too high a dosage for me, and I ended up spending the night in the hospital on IV fluids. The niphedipine brought my BP down quickly. But as the tyramine reaction subsided, the nifedipine just kept lowering my BP.

The literature demonstrating sublingual nifedipine used 10mg. Still, I wonder if that is too much based upon what you have described. Maybe chlorpromazine is the better way to go. I don't know what dosage is appropriate, though. I believe it works as a NE alpha-1 antagonist. Perhaps prazosin would be equally effective. I don't think it has been investigated for this purpose.


- Scott

 

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