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Re: MAOI's and blood pressure meds

Posted by SLS on August 2, 2006, at 23:33:21

In reply to MAOI's and blood pressure meds, posted by H. Upmann on August 2, 2006, at 21:27:19

> Just curious if it is common practice for a doctor to prescribe a blood pressure lowering med as a prophylactic in case you mess up your diet or eat something you wouldn't suspect to cause a reaction. My doc says just go to the ER as it's a bad idea to self-medicate when it comes to your blood pressure. Seems like if your in the middle of nowhere or alone and have a reaction you'd be SOL. Just curious what your docs have said if you've been prescribed Nardil or Parnate.


The gold standard of treatments for a tyramine reaction is phentolamine. Unfortunately, it is no longer available as an oral preparation. However, it is the best treatment available in the ER as intravenous Regitine. Phentolamine was being looked at for treating erectile dysfunction a few years back. It would have been nice to have it handy in case of emergencies.

I carry a nifedipine capsule around with me whenever I'm on a MAOI. There is some debate as to how desireable it is to use the sublingual preparation, however, this is the route most often chosen to study in medical literature. I haven't really investigated other alternatives. Chlorpromazine is used, but the sedation and EPS make it unattractive to me. It might be a more effective antidote, though.


- Scott

 

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