Posted by octopusprime on August 2, 2006, at 10:25:45
In reply to Meds and pregnancy (not me), posted by maxime on August 1, 2006, at 20:08:42
Prescribing information sheet for Prozac: http://pi.lilly.com/prozac.pdf
Note the following: "Treatment of Pregnant Women During the Third Trimester
Neonates exposed to Prozac and other SSRIs or SNRIs, late in the third trimester have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding (see PRECAUTIONS). When treating pregnant women with Prozac during the third trimester, the physician should carefully consider the potential risks and benefits of treatment. The physician may consider tapering Prozac in the third trimester."Prozac is category C, which means that further studies on fetal safety are necessary (ie the drug has not been proven safe or unsafe for fetuses).
Prescribing information sheet for Wellbutrin: http://us.gsk.com/products/assets/us_wellbutrinSR.pdf
Wellbutrin is also category C. The PI sheet has information about a pregnancy registry, which she should join. She can call and ask for additional information about wellbutrin during pregnancy.
Prescribing information sheet for Concerta: http://www.concerta.net/active/mccus/en_US/html/concerta/utilities/patient_info.pdf#zoom=100
Concerta is also category C.
She should call her pdoc immediately and tell him/her that she is pregnant and ask for advice on the continuation of this medication. Many women take category C medication during pregnancy without harm to the fetus. That said, there is no definitive proof that the medication is safe for the fetus.
Your friend may be stable enough to consider weaning off the medication to avoid any possible risk to the baby. If the benefits of medication outweigh the risk, then she can continue taking the meds. If I were her, I would consider going off the Prozac, staying on Wellbutrin, and then staying on Concerta. I might also consider finding a non-SSRI substitute for Prozac. Personally, I took Lamictal (another category C drug) through both my pregnancies. I miscarried the first at 11 weeks, and I am now at 20 weeks with the second. With this pregnancy the triple screen and the ultrasounds are showing no increased risk of birth defects/no signs of birth defects.
Congratulations to your friend and good luck making a decision.
poster:octopusprime
thread:672702
URL: http://www.dr-bob.org/babble/20060802/msgs/672895.html