Posted by Jost on June 8, 2006, at 23:08:02
In reply to Re: MAOI and epinephrine, posted by Karen44 on June 8, 2006, at 22:39:25
My pdr doesn't address the issue of epinephrine directly, but says under parnate:
"12. In Patients undergoing elective surgery
Patients taking parnate....should not be given...local anesthesia containing sympathomimetic vasoconstrictors..." (p. 3113)
Under epinephrine (Epipen) it says:
"Epinephrine is a sympathomimetic drugs.. The strong vasocontrictor action of epinephrine through its effect on alpha adrenergic receptors....." (p.1122)
From this I conclude that since epinephrine is a sympathomimetic vasoconstrictor, it shouldn't be given to patients taking parnate.
There could be more recent studies suggesting that in certain cases or with supervision at certain doses, this combination isn't life-threatening, or even necessarily dangerous. (My pdr is from 2001.) But my Pdoc definitely strongly advised me to avoid it--and without sophisticated attention, I'd be afraid to be in that position.
Jost
poster:Jost
thread:654285
URL: http://www.dr-bob.org/babble/20060604/msgs/654696.html