Posted by yxibow on June 7, 2006, at 2:48:02
In reply to Re: SEROQUEL versus ZYPREXA?, posted by blueberry on June 6, 2006, at 18:46:13
> Seroquel was way too stupifying and sedating for me. It also didn't last long enough. I had to take it every 3 hours because the anti-anxiety wore off too fast. Zyprexa is not that sedating and lasts a lot longer, needing only one dose a day though sometimes two is better.
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> Seroquel made me feel very depressed and lousy the next day. Dysphoric. While seroquel was depressing, zyprexa seems to be a mild antidepressant.
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> Seroquel gave me restless legs syndrome.
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> Zyprexa makes my hands jitter a little bit like parkinson's, but only after 12 hours since my last dose. If my hands are jittery, they calm down to perfectly still after a dose.
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> Clozapine is supposed to be the gold standard of antipsychotics and zyprexa is the closest thing to it. I consider seroquel to be just a super strong short acting version of remeron.
Seroquel has only a half life of 6 hours which means that it may need a twice daily dose in some individuals -- most though on a high enough dose need only a single night time dosing.And yes, Zyprexa can cause pseudoparkinsonism like I had mentioned -- it got to me that I couldn't function with power tools and other things that shake my hands to the point where all my fingers were shaking. It was too much. Disappointing because Zyprexa made benzodiazepines superfluous, it was calming.
There are similarities between Seroquel and Remeron in the 5HT blockade -- Remeron actually helped my disorder before I switched to Seroquel due to the massive weight gain.
Clozapine and Zyprexa are closely related but Clozapine has two major things against it -- one, 2% must discontinue because of low white blood cell counts, and there are other unpleasant side effects, I believe incontinence and various bodily symptoms that though it is a gold standard for some serious schizophreniform disorders, it is not without risk and heartache for the patient.
poster:yxibow
thread:653412
URL: http://www.dr-bob.org/babble/20060604/msgs/653916.html