Posted by lunesta on August 25, 2005, at 4:05:11
In reply to Dextromethorphan Glutamate? Connection?, posted by Empathy on August 25, 2005, at 2:15:42
Most physiatric diseases have this problem of excess glutamate which is basically our learning/stimulating neurotrainsmitter in the body/brain.
Its either too much glutamate, or too little gaba /magnesium which oppose (opposites) o glutamate.
MOST meds talked about here block some pathway o glutamate (a sodium channel, or calicum channel etc..)
OR if you use benzos etc.. your augmenting your inhibitory vs glutamate.
The ultimate solution is probably finding a glutamqate antgonist but remember that you need to glutamate to survive and to be functional and learn etc. So it is a fine balance of inhbition vs stimulation that gets upset in most of our disorders.
DXm is an NMDA antagonist. NMDA is excitatory, opposed by gaba and magnesium.
DXM also eects sigma receptors i believe.
poster:lunesta
thread:546405
URL: http://www.dr-bob.org/babble/20050821/msgs/546429.html