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Re: is there truly a diffrence between Brand Generic

Posted by 2ndXround on July 2, 2004, at 4:05:52

In reply to is there truly a diffrence between Brand Generic, posted by 1980Monroe on June 28, 2004, at 21:55:03

Hi
The 'King' said it very well. The absorbtion rate (bioequivalence) can be changed due to the inert ingredients.
Also, generics, when tested, do not have the exact bioequivalence of brand names. They have to come within a certain range of the brand names. I believe there is a +-15%-20% range of acceptance.
So in effect, a brand name could actually be 15-20% stronger or 15-20% weaker then the name brand.
I work in Cardiac Care and we are very careful about making sure we do not substitute generics for certain meds....like digoxyn. Exact dosage and timing is critical to the lives of many patients taking heart meds.


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