Re: why are benzo's considered superior?

Posted by 1980Monroe on June 28, 2004, at 21:41:22

In reply to Re: are barbiturates still in use? » 1980Monroe, posted by chemist on June 28, 2004, at 3:08:15

despite the toxity, does "superior" just mean overall better in general effects?
Chemist, this should be a breeze to you so you tell if im wrong, but i belive barbitureates work by opening calcium ion channels, which is maybe why they bring more sedating action than the benzodiazpenines, which only enhance GABA actity but have do not directly effect the ion channels. They both have their specific receptor on the GABA receptors, which the barbiturate receptor are in the inner ring of the channels and is why they open them, benzo's are on the outer top part and dont manipulate the opening, maybe thats why there not toxic.,
i heard barbiturates actualyl can act as GABA at high doses which is intresting.
But if there more sedating, than why are not considered superior?
Matt

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are barbiturates still in use? 1980Monroe 6/27/04
barbiturates anxiety_free 6/27/04
Re: are barbiturates still in use? » 1980Monroe chemist 6/28/04
Re: why are benzo's considered superior? 1980Monroe 6/28/04
Re: why are benzo's considered superior? » 1980Monroe chemist 6/29/04
Re: are barbiturates still in use? Cecilia 6/29/04
Re: why are benzo's considered superior? » 1980Monroe Shawn. T. 6/29/04
Re: are barbiturates still in use? » 1980Monroe jerrympls 6/29/04
Re: why are benzo's considered superior? 1980Monroe 7/2/04

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