Posted by King Vultan on June 28, 2004, at 15:13:59
In reply to Re: Is Anyone Doing Ok on Nardil for Depression, posted by Steven B on June 28, 2004, at 13:14:26
If I remember correctly, I started out at 3 x 15 mg/day for a couple of weeks, then went to 60 mg/day for either two or three weeks, then to 75 for about three weeks. I've been on 90 mg/day for a couple of months. It takes less than week for me to notice a dosage change--maybe four days--so it was over a month after starting the Nardil before I gained any real therapeutic effects (as stated in my previous post, this was at 75 mg/day--YMMV). Add onto that the two week washout period before the start date plus the amount of time I spent tapering down from my old med, and it really got to be quite a long stretch operating on essentially nothing.
As for taking my pills, believe it or not, I actually take them separately throughout the day. I've read that you may get more efficient MAO inhibition by spreading the dose throughout the day, and since this is how my doctor would prefer that I take them, anyway, and I am a relatively gung ho patient, it's not a big deal for me. Currently I take one each at 6 AM, 9-10 AM, 12 noon, 2-3 PM, 5-7 PM, and 11 PM.
As I stated, the stuff is working pretty well, but I also have some indications that my dose may be just a bit subtherapeutic. My mood is pretty good, but I still have a fair amount of anhedonia. I know Parnate would likely be better for that one particular characteristic, but I feel the Nardil is too beneficial otherwise to give up on at this point. In view of that and this reformulation/effectiveness issue, I'm seeing my pdoc next week about going up to 105 mg/day. He's told me that he has gone up this high in the past, and I am relatively certain he will agree to let me go ahead with it.
Todd
poster:King Vultan
thread:361254
URL: http://www.dr-bob.org/babble/20040627/msgs/361392.html