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Re: IMIPRAMINE? AT WHAT DOSE DOES NE REUPTAKE OCCUR??

Posted by francesco on March 28, 2004, at 13:52:09

In reply to IMIPRAMINE? AT WHAT DOSE DOES NE REUPTAKE OCCUR??, posted by aazospiro on March 28, 2004, at 13:00:39

> I read somewhere that a considerable amount of imipramine is metabolized to desipramine on first pass. Can NE reuptake occur at low doses? Example 12.5 mg? The reason I asked is that it seems to calm me down quite abit without ANY drowsiness. But its a stimulated calmness. I was VERY surprised because amitriptyline made me very very drowsy and heavy. ANYONE KNOW OF ANY SITES WITH DIFINATIVEINFORMATION ON THE FUNDAMENTAL DIFFERENCES ON THESE TRICYCLIC AGENTS?

I have no info about it but my experience. I found even 10mg of Imipramine very energizing but experience also agitation while on it. I had to quit for this reason even if I like it. According to the charts it has also SE-reuptake properties.
Francesco


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