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Re: Lithium/Moclobemide not working for Bipolar

Posted by Canyon on March 27, 2004, at 14:14:26

In reply to Re: Lithium/Moclobemide not working for Bipolar, posted by Keith Talent on March 27, 2004, at 1:45:00

> What matters with lithium is the concentration in the blood, not the dose. What was your concentration the last time it was measured? I tried moclobemide once for depression at 900mg/day. It was absolutely useless. I suspect that's why it's never been approved by the US FDA.

Thanks for that. My measured concentrations have consistantly been in the 0.8 and 1.2 mmol/L range, usually between 0.8-1.0 mmol/L when measured 12 hours out from ingestion. Interesting about Moclobemide. I will look at switching AD.


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