Posted by socialdeviantjeff on November 6, 2003, at 0:24:41
Well, it's me again. Stil having trouble with drugs. In case you never read any of my other sometimes irrational posts, here is the run-down:
4 different SSRI's, 2 TCA's, Wellbutrin, Neurontin, Lithium, and Tegretol. Some alone and some in combos (breaking it down would take too much time),over eight different drug trials. All of the trials were of adequate legnth of time except for two, which were abruptly cut short by severe allergies to the meds, and some others because of major side effects after a couple days or weeks. With every round, there was no imrovment, worse symptoms, or debilitating side effects (even on super low doses).
natural cures (insotil, St johns wort, 5-htp, etc) have done nothing.
I've noticed the more theraputic value a drug or combo the drug would have for me, the worse the side-effects were. That doesn't say much because the help I have received is at best less than 10% improvement after 5 weeks.
I can't find any personal experience that relates to mine. I haven't found any publications either. My pdoc has even said that I am the first person in his 30+ years of practice to reject so many different drugs so quickly and with such acute signs toxicity. He has gone as far to admit that my problems may be incurable.
From what I could find, there a few ideas I've been researching. A lot of these seem pretty far-fetched, and maybe invalid.
possible enzyme problem
asperger's or some other HLA
some milder kind of Anticholinergic syndrome or cholinergic syndrome
Hyperparathyroidism (my PTH is high)I'm on 200 mg/day Tegretol I take at night and 37.5 mg/day of effexor in the morning. I've only been on effexor for two days, amd I already have nausea, tremors, lightheadedness, amd my heart feels like it's beating faster.
FYI, I have never done drugs. Although I am a pretty heavy smoker, especially in the last 6 months. I rarely drink. I've never OD'd intentionally or accidentally.
Any other ideas? Anyone out there with a similar story? Any other direction I could look? Thanks in advance....
poster:socialdeviantjeff
thread:277035
URL: http://www.dr-bob.org/babble/20031105/msgs/277035.html