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try cutting out the tyrosine » Ame Sans Vie

Posted by Michael Bell on June 4, 2003, at 22:49:29

In reply to Klonopin withdrawal for first time.... why???, posted by Ame Sans Vie on June 4, 2003, at 9:49:08

>Sorry, I don't have much experience with Klonopin, but I do have a lot with tyrosine. Without a GABA drug like Klonopin to offset the effects, Tyrosine will definitely cause agitation and anxiety. At one time I was taking high doses of tyrosine with nothing else, and eventually I became extremely agitated, anxious and somewhat delusional. Also, any other dopaminergic drugs (l-carnitine, perhaps) are likely to contribute to anxious feelings. I'm not sure if Mirapex would cause anxiety, b/c dosns't it work like amisulpride? Low dose amisulpride decreases dopamine release & increases dopamine transmission (by interfering with the feedback loop). Then again Mirapex is serotogenic as well (i think), so who knows. Cut back completely on caffeine & soda, as well as foods high in sugar. And finally, try adjusting your picamilon doses (remember LOW doses are tranquilizing, so you may have to decrease your dosage). Good luck!


This is very strange and disturbing, as I've just started working after two years housebound. I ran out of my Klonopin a few days early, as the doctor told me I could take an extra one or two now and then for the added stress of my new job. But the pharmacy won't refill my prescription for a few days, and they can't call my doctor to get permission because he's on vacation.
>
> I've quit Klonopin cold turkey many times before, at this same dose (8mg / day) and even higher. I've never had withdrawal. So why now? Could there be any explanation for this? Or is it just one of those medication anomalies?
>
> I feel so tired... I just want to sleep, but I have to work. I feel queasy, and can't eat well. And of course, the anxiety has returned. All I can venture to think is that it may be a result of the other medications I now take with Klonopin, Mirapex in particular. Could this be the culprit? Or the supplements I take--picamilon, Enada NADH, niacinamide, pregnenolone, L-tyrosine, P-5-P, acetyl L-carnitine, selenium, vitamin C, sublingual liquid B-complex... my daily multivitamin even?? I'm just looking for some sort of answer. Maybe raising my dose of niacinamide will help curb the withdrawal symptoms? I already take the recommended dose for anxiety relief/benzo withdrawal (500mg qid), but supposedly it's okay to go higher.
>
> Please, any information would be *so* appreciated--this is awful!!


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Psycho-Babble Medication | Framed

poster:Michael Bell thread:231340
URL: http://www.dr-bob.org/babble/20030604/msgs/231516.html