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Re: Mifepristole (RU-486) lowers cortisol? » Ame Sans Vie

Posted by Pfinstegg on February 3, 2003, at 10:25:11

In reply to Mifepristole (RU-486) lowers cortisol?, posted by Ame Sans Vie on February 2, 2003, at 21:04:29

Yes, it does. There are presently studies going on at NIH and Stanford on both bipolar and unipolar depression, including patients with elevated 24-hour urinary cortisols and psychotic features. The first study, done at Stanford, on psychotically depressed patients, showed dramatic remissions with 7-10 days of mefipristone treatment, so the two present studies have been widened to include less ill patients. It is the only AD which has been promising enough to be "fast-tracked" by the FDA- they did that last August. People who are interested can join the large study now going on at NIH; as of December, 2002, they were still recruiting new patients.

Pfinstegg


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poster:Pfinstegg thread:139015
URL: http://www.dr-bob.org/babble/20030130/msgs/139095.html