Posted by disney4 on February 2, 2003, at 19:59:46
In reply to Re: Taking the plunge---Buspar tomorrow » jflange, posted by SLS on February 1, 2003, at 13:34:39
The 5-HT 1A agonist-action of Buspar makes all the difference for me.
Don't forget that the major metabolite of Buspar is a potent NE-alpha2 antagonist, as is Remeron.
I really didn't know that Remeron and Buspar shared that in common, but I did read that Buspar has 3 main modes of action..1) a serotonin modulator, 2) has a moderate affect on NE, and 3) has a mild affect on dopamine.
Is this what you have heard too?
> Without it I probably could not tolerate any ssri; while on it, I am happily taking Zoloft.What is it about SSRIs that you could not tolerate?
For each one it was a little different. Celexa and Lexapro both, made me edgy and anxious. Paxil made me feel like I was hit by a truck. Luvox made me sooooo sleepy. I never got around to trying Paxil, but I didn't want to suffer through the sexual SE's that they all shared in common for me, even the atypical Serotonin Agonist Serzone, which I took for a short time at a very low dose. By the way, the main SE's I have so far from Buspar at a starting does of 15 mg, divided into 3 daily doses is nausea and dizziness. At times I get a mild headache as well. Did you experience this, and if so how long did they take to subside? I am not feeling much of a change yet in my mental state, other than a little more motivation, which is giving me some hope.
poster:disney4
thread:138455
URL: http://www.dr-bob.org/babble/20030130/msgs/138996.html