Posted by zeugma on February 1, 2003, at 14:33:44
In reply to Re: Taking the plunge---Buspar tomorrow » jflange, posted by SLS on February 1, 2003, at 13:34:39
> Hi.
>
> > The 5-HT 1A agonist-action of Buspar makes all the difference for me.
>
> Don't forget that the major metabolite of Buspar is a potent NE-alpha2 antagonist, as is Remeron.
>
> > Without it I probably could not tolerate any ssri; while on it, I am happily taking Zoloft.
>
> What is it about SSRIs that you could not tolerate? Had you tried Zoloft without Buspar?
>
>
> - ScottI am someone who could not tolerate Zoloft; exactly why, I can't remember, this was a period when I was going through the 'standard' meds for ADD and depression, and there were severe probs attendant on each. My starter pack of Zoloft was barely touched, so it must have been something dramatic (and fast). Anyway I have read here that Buspar decreases serotonin levels; is this true? Could that be why some people who can't tolerate SSRI's like Buspar, and vice versa? After more than a month on Buspar, I feel the closest to 'well' that I have ever felt in my life (I'm 35).
poster:zeugma
thread:138455
URL: http://www.dr-bob.org/babble/20030130/msgs/138756.html