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Re: does effexor go with lithium

Posted by SLS on February 1, 2003, at 13:26:02

In reply to does effexor go with lithium, posted by linkadge on January 30, 2003, at 6:39:49

> I tried effexor by itself but now since
> bipolar diagnosis was wondering
> if effexor would be any different.
>
> Linkadge


I think that adding lithium to any antidepressant is a valid treatment. Rarely, however, combining lithium with SSRIs or Effexor has produced "serotonin syndrome". This can be serious if not recognized early.


-------------------------------------------


The symptoms of serotonin syndrome include the following:

Mental status changes
Confusion (51%)
Agitation (34%)
Hypomania (21%)
Anxiety (15%)
Coma (29%)

Cardiovascular
Sinus tachycardia (36%)
Hypertension (35%)
Hypotension (15%)

Gastrointestinal
Nausea (23%)
Diarrhea (8%)
Abdominal pain (4%)
Salivation (2%)

Motor Abnormalities
Myoclonus (58%)
Hyperreflexia (52%)
Muscle rigidity (51%)
Restlessness (48%)
Tremor (43%)
Ataxia/incoordination (40%)
Shivering (26%)
Nystagmus (15%)
Seizures (12%)

Other
Diaphoresis (45%)
Unreactive pupils (20%)
Tachypnea (26%)
Hyperpyrexia

 

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