Posted by JohnX2 on February 24, 2002, at 17:25:37
wondering if anyone experienced severe
anxiety on pindolol (visken)?Pindolol is a partial beta agonist and
is supposed to block excessive noradrenergic
transmission, but the medicine made me extremely
anxious.This is compared to propranolol (Inderal) which
is a full beta blocker and made me calm.What I'm wondering is if this implies that
the pindolol is actually augmenting a hyponoradrenergic
state in the synaptic cleft. The medication actually
mades me hypomanic after 3 days, then petered out
in 1 hr. worked like this twiced. i suspect a catecholamine
depletion. My depression lifts are always accompanied by
caffeine or excersize which increases cortisol and
the nor(adrenergic) response. But alas I think some
malfunctioning feedback loop stops the ball game.
I've been reading how noradrenergic meds will poop out
if crappy feedback causes a post response monoamine depletion
(big surprise).Anyone else get edgy on Pindolol?
-John
poster:JohnX2
thread:95338
URL: http://www.dr-bob.org/babble/20020222/msgs/95338.html