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Re: MAOI transdermal patches-what's the status? » Joe Schmoe

Posted by Mitch on August 26, 2001, at 17:48:57

In reply to Re: MOST EFFECTIVE MED FOR SOCIAL PHOBIA!, posted by Joe Schmoe on August 26, 2001, at 9:15:39

> It sounds like the problems Nardil causes are in the body while the benefits are in the brain.
>
> The scientists need to develop some way to make a MAOI that only works in the brain and is not utilized by the rest of the body. Maybe some second pill that you take an hour later that destroys the MAOI, but that cannot cross the blood-brain barrier.


There are transdermal patches of phenelzine, and I believe tranylcypromine (parnate), that are supposed to be in clinical studies right now. I would really want to try an MAOI, but my doc says NO. The patches are supposed to be a way of bypassing the gut so you don't have the diet restrictions, but still would have to be cautious about drug interactions. Does anybody know what the status of these patches is??


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