Posted by phillybob on August 25, 2001, at 22:25:28
In reply to 300mg of FXR *100mg Wellbutrin SR**too much??, posted by DebbieLynn on August 25, 2001, at 15:27:56
I had built up and then been steady (with occassional increases to 300 mg/day) on the 225 mg/day FXR dose for about 3 weeks. The last 2 weeks on that dose, I added 150 mg/twice daily (300mg total daily) of Wellbutrin to help with energy.
The first week was quite nice, but the second week, I did have frequent urination and, in fact, a non-urine discharge when urinating. I re-called a similar problem before with Wellbutrin alone. Needless to say, I stopped the Wellbutrin (and pretty close thereafter, the Effexor, for other reasons which I'm too tired to even go into right now).
Just off-hand, if the Effexor is benefiting you, I'd probably stay with that and kill the WB. But, you might want to check on whether that's a WB side-effect that'll go away.
While weight gain is an almost automatic issue, Remeron might be a good adjunct for sexual function (?). Check that out, but I suppose serotonin syndrome would have to be more carefully monitored with that combo. [I had a good experience with Remeron but then ... see my last paragraph.]
It does not, though, seem as if the FXR/WB combo would result in serotonin syndrome for the same reasons you've already stated.
I personally just have these serotonin syndrome-like reactions to many meds after being on them for a while, whether alone or in combo with something.
Best wishes.
poster:phillybob
thread:76374
URL: http://www.dr-bob.org/babble/20010822/msgs/76416.html