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Re: effexor+paxil help???

Posted by Andre Allard on August 24, 2001, at 18:39:40

In reply to effexor+paxil help???, posted by johnjones on August 22, 2001, at 14:03:02

You will not find a pdoc that will prescribe both venlafaxine and an SSRI. The reason is that they both of the AADs act on serotonin in very similiar ways.

Paxil tends to be the worst among the SSRI's for sexual dysfunction. Any AD that works on 5HT2A I believe, hinders one's sex life.

Bupropion does not impede on sexual function and can even augment it. The catch is that bupropion does not have the same efficiousy rate in severe depression as the SSRI's and venlafaxine. Bupropion is also not as broad spectrum as most other ADs.

From my experience, trazadone (100mg/night) does help somewhat. There are other meds that have been studied for sexual dysfunction but the results have been inconclusive.

Even though my libido has dropped significantly and I take a lot longer to ejaculate on 450mg venlafaxine, it sure as hell beats not having a libido and not being able to ejaculate when I am off of all meds and in a deep depression.

Good luck!


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